The Republican president, who has also revoked the security clearance for former President Joe Biden, defeated Clinton in the 2016 presidential election and Harris in last year's election.
"I have determined that it is no longer in the national interest for the following individuals to access classified information," Trump said in a late Friday memorandum that also included former Secretary of State Antony Blinken.
While the revocations may not have immediate impacts, it is another sign of the growing political rift in Washington as Trump seeks revenge on his perceived enemies.
The memorandum was issued hours after Trump arrived at his Bedminster, New Jersey, golf property for the weekend.
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